Monitoring Incidence of COVID-19 Cases, Hospitalizations, and Deaths, by Vaccination Status — 13 U.S. Jurisdictions, April 4 – July 17, 2021

"The incidence of SARS-CoV-2 infection, hospitalization, and death is higher in unvaccinated than vaccinated persons, and the incidence rate ratios are related to vaccine effectiveness. Across 13 U.S. jurisdictions, incidence rate ratios for hospitalization and death changed relatively little after the SARS-CoV-2 B.1.617.2 (Delta) variant reached predominance, suggesting high, continued vaccine effectiveness against severe COVID-19. Case IRRs decreased, suggesting reduced vaccine effectiveness for prevention of SARS-CoV-2 infections. Getting vaccinated protects against severe illness from COVID-19, including the Delta variant. Monitoring COVID-19 incidence by vaccination status might provide early signals of potential changes in vaccine effectiveness that can be confirmed through robust controlled studies." - United States Centers for Disease Control and Prevention 

Additional Authors: David Blythe, Shane Brady, Betsy Cadwell, Iris Cheng, Sherri Davidson, Janelle Delgadillo, Katelynn Devinney, Jeff Duchin, Monique Duwell, Rebecca Fisher, Aaron Fleischauer, Ashley Grant, Jennifer Griffin, Meredith Haddix, Julie Hand, Matt Hanson, Eric Hawkins, Rachel K. Herlihy, Liam Hicks, Corinne Holtzman, Mikhail Hoskins, Judie Hyun, Ramandeep Kaur, Meagan Kay, Holly Kidrowski, Curi Kim, Kenneth Komatsu, Kiersten Kugeler, Melissa Lewis, B. Casey Lyons, Shelby Lyons, Ruth Lynfield, Keegan McCaffrey, Chelsea McMullen, Lauren Milroy, Stephanie Meyer, Leisha Nolen, Monita R. Patel, Sargis Pogosjans, Heather E. Reese, Amy Saupe, Jessica Sell, Theresa Sokol, Daniel Sosin, Emma Stanislawski, Kelly Stevens, Hailey Vest, Kelly White, Erica Wilson, Adam MacNeil, Matthew D. Ritchey, Benjamin J. Silk